INTEDE: Full Data Download

Download the Metabolic Roadmap of Drug and Drug-Metabolizing Enzyme (DME) (2024 Update)

a. Drug-Metabolizing Enzyme (DME)
    Sequential Position of DMEs involved in Metabolic Roadmap of All Drug Click to Save
b. Metabolic Reactions
    Stepwise Metabolic Reactions During Drug Metabolism Click to Save
c. Drug Metabolites
    Drug Metabolites with Diverse Structure, Pharmacological Activity and Toxicity Click to Save

Download the Interactome Data of Drug-Metabolizing Enzyme (DME)

a. Interactions between Microbiome and Drug-Metabolizing Enzyme (MICBIO)
    Microbiome-host DME interaction data (microbiome species name / co-effect drug and result / microbiome family, phylum, etc) Click to Save
b. Interactions between Xenobiotics and Drug-Metabolizing Enzyme (XEOTIC)
    Xenobiotics factors (health or environmental toxicant / natural product / extract or medicine, etc) altering DME activity Click to Save
c. Interactions between Host Protein and Drug-Metabolizing Enzyme (HOSPPI)
    Host protein-DME interaction data (Histone & Non-coding RNA & Transcription-factor regulation / Oligomerization) Click to Save
    Host protein-DME interaction data (DNA methylation) Click to Save

Download the Data of Sequence, Structure, Function and Cross-matching

Drug-Metabolizing Enzyme (DME)
    Sequence (FASTA format) and structure (PDB file) data of DMEs Click to Save
    Metabolizing enzyme-drug affinity data Click to Save
    Tissue-distribution and function data of DMEs Click to Save
    Complete EC Tree of DMEs Click to Save
Drugs Metabolized by DMEs
    2D structure data (SDF format) for the drugs metabolized by DMEs Click to Save
    3D structure data (SDF format) for the drugs metabolized by DMEs Click to Save
    SMILES and InChI for the drugs metabolized by DMEs Click to Save
    Physicochemical properties for the drugs Click to Save
Xenobiotics that affects DMEs
    2D structure data (SDF format) for the xenobiotics that affects DMEs Click to Save
    3D structure data (SDF format) for the xenobiotics that affects DMEs Click to Save
    Sequence for the xenobiotics that affects DMEs Click to Save
Synonyms and Cross-matching
    Cross-matching ID between the DMEs and a variety of public databases Click to Save
    Synonyms of DMEs and their corresponding drugs Click to Save
    DMEs to disease mapping with International Classification of Diseases (ICD) identifiers Click to Save
    Drug to disease mapping with International Classification of Diseases (ICD) identifiers Click to Save

Last Update by

    Jun 29th, 2023

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