Details of Drug-Metabolizing Enzyme (DME)
| General Information of DME (ID: DME1463) | |||||
|---|---|---|---|---|---|
| DME Name | Unclear metabolic mechanism (DME-unclear), Slackia isoflavoniconvertens | ||||
| Gene Name | DME-unclear | ||||
| Lineage | Species: Slackia isoflavoniconvertens (Click to Show/Hide the Complete Species Lineage) | ||||
| Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME | |||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Full List of Drug(s) Metabolized by This DME | |||||
|---|---|---|---|---|---|
| Drugs in Phase 4 Clinical Trial | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
Daidzein |
Drug Info | Phase 4 | Dyslipidaemia | ICD11: 5C81 | [1] |
| Drugs in Phase 2 Clinical Trial | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
BIO-300 |
Drug Info | Phase 2 | Prostate cancer | ICD11: 2C82 | [1] |
| References | |||||
|---|---|---|---|---|---|
| 1 | Daidzein and genistein are converted to equol and 5-hydroxy-equol by human intestinal Slackia isoflavoniconvertens in gnotobiotic rats. J Nutr. 2012 Jan;142(1):40-6. | ||||
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