Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1468)
DME Name	Unclear metabolic mechanism (DME-unclear), Synergistetes bacterium
Gene Name	DME-unclear
Lineage	Species: Synergistetes bacterium (Click to Show/Hide the Complete Species Lineage) Kingdom: Bacteria Phylum: Synergistetes Class: Synergistetes Order: Synergistetes Family: Synergistetes Genus: Synergistetes Species: Synergistetes bacterium
Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution	Primarily distributed in human oral cavity.

Full List of Drug(s) Metabolized by This DME
Drugs Approved by FDA			Click to Show/Hide the Full List of Drugs: 1 Drugs
Sulfamethoxazole	Drug Info	Approved	Infectious cystitis	ICD11: GC00	[1], [2]

References
1	Bacterial community changes and antibiotic resistance gene quantification in microbial electrolysis cells during long-term sulfamethoxazole treatment. Bioresour Technol. 2019 Dec;294:122170.
2	Distributions of Synergistetes in clinically-healthy and diseased periodontal and peri-implant niches. Microb Pathog. 2016 May;94:90-103.

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