Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1737)
DME Name	Unclear metabolic mechanism (DME-unclear), Fusobacterium canifelinum
Gene Name	DME-unclear
Lineage	Species: Fusobacterium canifelinum (Click to Show/Hide the Complete Species Lineage) Kingdom: Bacteria Phylum: Fusobacteria Class: Fusobacteriia Order: Fusobacteriales Family: Fusobacteriaceae Genus: Fusobacterium Species: Fusobacterium canifelinum
Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution	Primarily distributed in human gut.

Full List of Drug(s) Metabolized by This DME
Drugs in Phase 2 Clinical Trial			Click to Show/Hide the Full List of Drugs: 1 Drugs
Q-100154	Drug Info	Phase 2	Hepatocellular carcinoma	ICD11: 2C12	[1]
Preclinical/investigative Agents			Click to Show/Hide the Full List of Drugs: 3 Drugs
Kalopanaxsaponin H	Drug Info	Investigative	Diabetes mellitus	ICD11: 5A10	[2]
Kalopanaxsaponin I	Drug Info	Investigative	Prostate cancer	ICD11: 2C82	[2]
Kalopanaxsaponin K	Drug Info	Investigative	Rheumatoid arthritis	ICD11: FA20	[2]

References
1	Interactions between various microbes and ginseng botanicals. Crit Rev Microbiol. 2011 May;37(2):113-20.
2	Metabolism of kalopanaxsaponin K by human intestinal bacteria and antirheumatoid arthritis activity of their metabolites. Biol Pharm Bull. 2002 Jan;25(1):68-71.

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