Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1764)
DME Name Unclear metabolic mechanism (DME-unclear), Bacteroides vulgatus
Gene Name DME-unclear
Lineage    Species: Bacteroides vulgatus     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides vulgatus
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut.
Full List of Drug(s) Metabolized by This DME
      Drugs in Phase 3 Clinical Trial Click to Show/Hide the Full List of Drugs:          1 Drugs
BV-ara-U
 Drug Info Phase 3 Human immunodeficiency virus infection ICD11: 1C60 [1]
References
1 Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil. Pharmacogenetics. 1997 Feb;7(1):35-43.

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