Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN150)
DME Name Dihydrodaidzein reductase (l-dhdr), Lactococcus garvieae
Gene Name l-dhdr
UniProt ID
E7FL41_9LACT
Lineage    Species: Lactococcus garvieae     (Click to Show/Hide the Complete Species Lineage)
Kingdom: .
Phylum: .
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Genus: .
Species: Lactococcus garvieae
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Sequence
MAQEVKVPKMPGAPVFGKWISPEESVGQRLKGKKILLTGTTKGVGRVTQELLCAHGAFVC
GSGRTPGVAASVADELKAKGYQAAGMDVDLSDYDAVKKWVEECAELMGGIDVVINNASHP
GMAPFGEMTPEIWNYGIKNELDLVYNVCNCAWPYLQKADGASIIITSSTVALQGSNSPQA
CHAACKGACLSLARQLAAEGGPFGIRCNSVTPGLVWTEAMSNIPKEMASGLVAAQTTQQA
VDPMDIAYAYLFLASDESRQITAANIPVDGGCAGAVTGGMQGEIEV
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Dihydrodaidzein
 Drug Info Investigative Discovery agent ICD: N.A. [1], [2]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR004165 Dihydrodaidzein Tetrahydrodaidzein Unclear - Unclear Dihydrodaidzein [1], [2]
References
1 Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium
2 P212A Mutant of Dihydrodaidzein Reductase Enhances (S)-Equol Production and Enantioselectivity in a Recombinant Escherichia coli Whole-Cell Reaction System

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