Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN160)
DME Name Glutamine-dependent NAD(+) synthetase (QNS1), Saccharomyces cerevisiae
Gene Name QNS1
UniProt ID
NADE_YEAST
EC Number    EC: 6.3.5.1     (Click to Show/Hide the Complete EC Tree)
Ligase
Carbon-nitrogen ligase
Carbon-nitrogen ligase
EC: 6.3.5.1
Lineage    Species: Saccharomyces cerevisiae     (Click to Show/Hide the Complete Species Lineage)
Kingdom: .
Phylum: .
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Genus: .
Species: Saccharomyces cerevisiae
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Sequence
MSHLITLATCNLNQWALDFEGNRDRILQSIKIAKERGARLRVGPELEITGYGCLDHFLEN
DVCLHSWEMYAQIIKNKETHGLILDIGMPVLHKNVRYNCRLLSLDGEILFIRPKIWLAND
GNYREMRFFTPWMKPGVVEDFILPPEIQKVTGQRLVPFGDAVINSLDTCIGTETCEELFT
PQSPHIAMSLDGVEIMTNSSGSHHELRKLNKRLDLILNATKRCGGVYLYANQRGCDGDRL
YYDGCALIAINGTIVAQGSQFSLDDVEVVTATVDLEEVRSYRAAVMSRGLQASLAEIKFK
RIDIPVELALMTSRFDPTVCPTKVREPFYHSPEEEIALGPACWMWDYLRRCNGTGFFLPL
SGGIDSCATAMIVHSMCRLVTDAAQNGNEQVIKDVRKITRSGDDWIPDSPQDLASKIFHS
CFMGTENSSKETRNRAKDLSNAIGSYHVDLKMDSLVSSVVSLFEVATGKKPIYKIFGGSQ
IENLALQNIQARLRMVLSYLFAQLLPWVRGIPNSGGLLVLGSANVDECLRGYLTKYDCSS
ADINPIGGISKTDLKRFIAYASKQYNMPILNDFLNATPTAELEPMTKDYVQSDEIDMGMT
YEELGVFGYLRKVEKCGPYSMFLKLLHQWSPKLTPRQISEKVKRFFFFYAINRHKQTVLT
PSYHAEQYSPEDNRFDLRPFLINPRFPWASRKIDEVVEQCEAHKGSTLDIMSID
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
D-ribosylnicotinate
 Drug Info Investigative Discovery agent ICD: N.A. [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR012862 NaAD+ NAD+ Unclear - Unclear D-ribosylnicotinate [1]
MR012862 NaAD+ NAD+ Unclear - Unclear D-ribosylnicotinate [1]
References
1 Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism

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