| General Information of DME (ID: DMEN276) |
| DME Name |
17beta-hydroxysteroid dehydrogenase (HSD17B), Homo sapiens
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| Gene Name |
HSD17B
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| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Full List of Drug(s) Metabolized by This DME |
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Drugs in Phase 4 Clinical Trial
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Click to Show/Hide the Full List of Drugs: 1 Drugs
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Prasterone sulfate |
Drug Info
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Phase 4 |
Adrenocortical deficiency
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ICD11: 5A74
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[1] |
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Drugs in Phase 3 Clinical Trial
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Click to Show/Hide the Full List of Drugs: 1 Drugs
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EPIANDROSTERONE |
Drug Info
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Phase 3 |
Discovery agent
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ICD: N.A.
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[2] |
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| Full List of Metabolic Reactions (MR) Catalyzed by This DME |
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| References |
| 1 |
Toxin and Toxin Target Database (T3DB):Prasterone sulfate
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| 2 |
Human liver S9 fractions: metabolism of dehydroepiandrosterone, epiandrosterone, and related 7-hydroxylated derivatives
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| 3 |
Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA)--recent reports
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