General Information of DME (ID: DMEN287)
DME Name 7-Hydroxysteroid dehydrogenase (7-HSDH), Bacteroides fragilis
Gene Name 7-HSDH
Lineage    Species: Bacteroides fragilis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides fragilis
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Oxolithocholic acid
Drug Info Investigative Discovery agent ICD: N.A. [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR006023 CA 7-oxo-DCA Unclear - Unclear Oxolithocholic acid [1]
MR006020 Oxolithocholic acid 7,12-dioxo-LCA Unclear - Unclear Oxolithocholic acid [1]
References
1 Metabolism of oxo-bile acids and characterization of recombinant 12alpha-hydroxysteroid dehydrogenases from bile acid 7alpha-dehydroxylating human gut bacteria. Appl Environ Microbiol. 2018 May 1;84(10). pii: e00235-18.

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