Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN350)
DME Name hydroxysteroid dehydrogenase (HSD), Homo sapiens
Gene Name HSD
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR007089 3alpha-OH-desogestrel 3-Ketodesogestrel Oxidation - Oxidationn Desogestrel [1]
MR007091 3beta-OH-desogestrel 3-Ketodesogestrel Oxidation - Oxidationn Desogestrel [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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