Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN367)
DME Name KIC dioxygenase (KICD), Homo sapiens
Gene Name KICD
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Drugs in Phase 2 Clinical Trial Click to Show/Hide the Full List of Drugs:          1 Drugs
GTPL-3312
 Drug Info Phase 2 Diamond blackfan anemia ICD11: 3A60 [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR007480 KIC(a-ketoisocaproate) HMB(beta-hydroxy-beta-methylbutyrate) Unclear - Unclear GTPL-3312 [1]
References
1 Leucine Supplementation: A Novel Strategy for Modulating Lipid Metabolism and Energy Homeostasis

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