Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN743)
DME Name Alcohol dehydrogenase (ADH), Homo sapiens
Gene Name ADH
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR008032 Ethambutol Ethambutol Aldehyde Oxidation - Alcohol dehydrogenation Ethambutol [1], [2]
MR008033 Methylergometrine 2,2'-(Ethylenediimino)di-butryic acid Oxidation - Aldehyde dehydrogenation Ethambutol [1], [2]
References
1 COMPARATIVE METABOLISM OF ETHAMBUTOL AND ITS L-ISOMER
2 Global Urine Metabolomics in Patients Treated with First-Line Tuberculosis Drugs and Identification of a Novel Metabolite of Ethambutol

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