Details of Drug-Metabolizing Enzyme (DME)
| General Information of DME (ID: DMEN789) | |||||
|---|---|---|---|---|---|
| DME Name | Perillic acid-CoA ligase GeoC (BN940_14101), Castellaniella defragrans 65Phen | ||||
| Gene Name | BN940_14101 | ||||
| UniProt ID | |||||
| EC Number | EC: 6.2.1.3 (Click to Show/Hide the Complete EC Tree) | ||||
| Lineage | Species: Castellaniella defragrans 65Phen (Click to Show/Hide the Complete Species Lineage) | ||||
| Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME | |||||
| Sequence |
MWLHTEITSLADIPRHYARTAGDRVALMSATRKMSWRELDLASNRLANLLIARGVPPGGI
VAFFGKNSIEYFIAIFGANKAGCALLPLNWRLAAPEQAAVLQDARPQTILVDAEYAEALR QAIEAGAPPAASIAFDSAGAQDTELADGLAQCSDADPRLAIRPEDTALLLYTSGTTGQPK GVQLTHGGLNYMRLCEHLEPSLAWRPDDIMMLVMPNFHMVGTGLSLQGLYNGVPLTILPA FEAGSVLAAIERDKATVCCLVPTTIQMLIDHPDAAKADLSSLRLIMYAGSPITAGLLGRA IQTIHCDFMQFYGATESGGAITLLRPEQHDLAAEKKLKSCGSPVPLIEVKVVSPSGDTLP DGEVGEFLVRSPTLFKGYLNKPELTRAAFSDGWYMTGDAGYRDQDGLLYLVDRTKDMIIT GGENVYSTEVESAISKHPGVSQVAVIGLPDSQWGERVVAIVVPAADACPTAEDIIAHCRR LIAAYKAPKQVVFANHLPMTPSGKILKATLRKQFREMAET |
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| Full List of Drug(s) Metabolized by This DME | |||||
|---|---|---|---|---|---|
| Discontinued/withdrawn Drugs | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
Perillyl alcohol |
Drug Info | Discontinued in Phase 2 | Solid tumour/cancer | ICD11: 2A00-2F9Z | [1] |
| Full List of Metabolic Reactions (MR) Catalyzed by This DME | ||||||||||||||||||||||||||||
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| References | |||||
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| 1 | The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen | ||||
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