General Information of DME (ID: DMEN071)
DME Name	Kinase (Ks), .
Gene Name	Ks
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Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF MR001408 Lamivudine Lamivudine monophosphate Other reaction - Phosphorylation lamivudine [1], [2] MR001404 Lamivudine monophosphate Lamivudine diphosphate Other reaction - Phosphorylation lamivudine [1], [2] MR010272 Telbivudine 5-triphosphate Unclear - Unclear Telbivudine [3] MR013482 Acyclovir diphosphate Acyclovir triphosphate Conjugation - Phosphorylation Valacyclovir Hydrochloride [4]

References
1	Model for intracellular Lamivudine metabolism in peripheral blood mononuclear cells ex vivo and in human immunodeficiency virus type 1-infected adolescents. Antimicrob Agents Chemother. 2006 Aug;50(8):2686-94.
2	Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine Antimicrob Agents Chemother. 2007 Jun;51(6):2130-5. doi: 10.1128/AAC.01543-06.
3	Pharmacokinetics of telbivudine in healthy subjects and absence of drug interaction with lamivudine or adefovir dipivoxil
4	DrugBank(Pharmacology-Metabolism):Valacyclovir Hydrochloride

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