Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN182)
DME Name Dye-decolorizing peroxidase AauDyP1 (dyp1), Auricularia auricula-judae
Gene Name dyp1
UniProt ID
DYP_AURAJ
EC Number    EC: 1.11.1.19     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Peroxidase
Peroxidase
EC: 1.11.1.19
Lineage    Species: Auricularia auricula-judae     (Click to Show/Hide the Complete Species Lineage)
Kingdom: .
Phylum: .
Class: .
Order: .
Family: .
Genus: .
Species: Auricularia auricula-judae
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Sequence
MRLSPVFVALLSGLLAADLGLARSVAPRVADSPAAVTGTRKTSLLKNVAGLPPVPSAAQV
AATSLNTDDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQ
PLVALNIAFSNTGLLALGVTDNLGDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVII
LASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHEMFGFLDGIAQPAINGFN
TPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSG
SLQARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHC
PFSAHIRKTRPRADLGGSLTPPNLSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAF
VAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNNGQPRVVNGLLPSNSSAS
LSIPQFVVSHGGEYFFSPPISAIGGRLSA
Structure
4AU9 ; 4UZI ; 4W7J ; 4W7K ; 4W7L ; 4W7M ; 4W7N ; 4W7O ; 5AG0 ; 5AG1 ; 5IKD ; 5IKG
Function Manganese-independent peroxidase that is able to convert a large number of compounds, but its physiological substrate is not known. In addition to classic peroxidase substrates (e.g. 2,6-dimethoxyphenol), oxidizes dyes such as Reactive Blue 5 and Reactive Black 5.
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Mononitrophenol
 Drug Info Investigative Discovery agent ICD: N.A. [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR012909 Mononitrophenol Mononitrophenol Metabolite A5 Oxidation - Oxidationn Mononitrophenol [1]
References
1 Different fungal peroxidases oxidize nitrophenols at a surface catalytic tryptophan

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