Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN183)
DME Name Versatile peroxidase VPL1 (vpl1), Pleurotus eryngii
Gene Name vpl1
UniProt ID
VPL1_PLEER
EC Number    EC: 1.11.1.16     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Peroxidase
Peroxidase
EC: 1.11.1.16
Lineage    Species: Pleurotus eryngii     (Click to Show/Hide the Complete Species Lineage)
Kingdom: .
Phylum: .
Class: .
Order: .
Family: .
Genus: .
Species: Pleurotus eryngii
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Sequence
MSFKTLSALALALGAAVQFASAAVPLVQKRATCADGRTTANAACCVLFPILDDIQENLFD
GAQCGEEVHESLRLTFHDAIGFSPTLGGGGADGSIIAFDTIETNFPANAGIDEIVSAQKP
FVAKHNISAGDFIQFAGAVGVSNCPGGVRIPFFLGRPDAVAASPDHLVPEPFDSVDSILA
RMSDAGFSPVEVVWLLASHSIAAADKVDPSIPGTPFDSTPGVFDSQFFIETQLKGRLFPG
TADNKGEAQSPLQGEIRLQSDHLLARDPQTACEWQSMVNNQPKIQNRFAATMSKMALLGQ
DKTKLIDCSDVIPTPPALVGAAHLPAGFSLSDVEQACAATPFPALTADPGPVTSVPPVPG
S
Structure
4BLK ; 4BLL ; 4BLN ; 4BLX ; 4BLY ; 4BLZ ; 4BM0
Function A versatile ligninolytic peroxidase that combines the substrate specificity characteristics of the two other ligninolytic peroxidases, manganese peroxidase and lignin peroxidase.
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Mononitrophenol
 Drug Info Investigative Discovery agent ICD: N.A. [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR012909 Mononitrophenol Mononitrophenol Metabolite A5 Oxidation - Oxidationn Mononitrophenol [1]
References
1 Different fungal peroxidases oxidize nitrophenols at a surface catalytic tryptophan

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