| General Information of Drug Metabolite (DM) (ID: DM000065) |
| DM Name |
7-hydroxydicumarol
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Beta-glucuronidase (GUSB)
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DME0106
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| Oxidation - Hydroxylation |
Dicumarol
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Dicumarol |
DR1746
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Approved |
Menorrhagia |
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| References |
| 1 |
Metabolism of dicumarol-14 C by rat-liver microsomes Pharmacol Res Commun. 1976 Oct;8(5):469-75. doi: 10.1016/0031-6989(76)90056-4.
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| 2 |
Determination of dicumarol metabolites in bile of rats J Pharm Sci. 1975 Jul;64(7):1158-62. doi: 10.1002/jps.2600640705.
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