Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM000172)
DM Name	Fesoterodine carboxy metabolite

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2D6 (CYP2D6)	DME0009	Fesoterodine 5-hydroxymethyl tolterodine	Unclear - Unclear	Fesoterodine	[1] , [2]
Cytochrome P450 3A4 (CYP3A4)	DME0001	Fesoterodine 5-hydroxymethyl tolterodine	Unclear - Unclear	Fesoterodine	[1] , [2]

Full List of Drug(s) That Produce This DM By Metabolism
Fesoterodine		DR0693	Approved		Overactive bladder

References
1	Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug-Drug Interaction for Fesoterodine When Coadministered With Mirabegron J Clin Pharmacol. 2019 Nov;59(11):1505-1518. doi: 10.1002/jcph.1438.
2	LABEL:FESOTERODINE FUMARATE tablet, extended release

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