Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM000762)
DM Name	Cenobamate metabolite M2a/2b

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
UDP-glucuronosyltransferase 2B4 (UGT2B4)	DME0047	Cenobamate	Conjugation - Glucuronidation	Cenobamate	[1]
UDP-glucuronosyltransferase 2B7 (UGT2B7)	DME0040	Cenobamate	Conjugation - Glucuronidation	Cenobamate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Cenobamate		DR0288	Approved		Focal seizure

References
1	Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects Eur J Drug Metab Pharmacokinet. 2020 Aug;45(4):513-522. doi: 10.1007/s13318-020-00615-7.

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