| General Information of Drug Metabolite (DM) (ID: DM001079) |
| DM Name |
Meclizine metabolite M2
|
| Structure |
|
|
3D MOL is unavailable
|
2D MOL is unavailable
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2D6 (CYP2D6)
|
DME0009
|
| Oxidation - Benzylic Oxidation |
Meclizine
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Meclizine |
DR1006
|
Approved |
Functional nausea/vomiting |
|
|
| References |
| 1 |
Meclizine metabolism and pharmacokinetics: formulation on its absorption. J Clin Pharmacol. 2012 Sep;52(9):1343-9.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
