| General Information of Drug Metabolite (DM) (ID: DM001257) |
| DM Name |
metabolites of pimecrolimus
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - O-Demethylation; Oxygenation |
Pimecrolimus
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Pimecrolimus |
DR1289
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Approved |
Atopic dermatitis |
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| References |
| 1 |
Pimecrolimus: absorption, distribution, metabolism, and excretion in healthy volunteers after a single oral dose and supplementary investigations in vitro. Drug Metab Dispos. 2006 May;34(5):765-74.
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