| General Information of Drug Metabolite (DM) (ID: DM002177) |
| DM Name |
Niclosamide-2-O-glucuronide metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Conjugation - Glucuronidation |
Niclosamide
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[1] |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Conjugation - Glucuronidation |
Niclosamide
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Niclosamide |
DR1146
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Approved |
Tapeworm infestation |
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| References |
| 1 |
Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1 Xenobiotica. 2016;46(1):1-13. doi: 10.3109/00498254.2015.1047812.
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