| General Information of Drug Metabolite (DM) (ID: DM002848) |
| DM Name |
5-hydroxypimozide
|
| Structure |
|
|
3D MOL is unavailable
|
2D MOL is unavailable
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2D6 (CYP2D6)
|
DME0009
|
| Oxidation - Hydroxylation |
Pimozide
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Pimozide |
DR1291
|
Approved |
Schizophrenia |
|
|
| References |
| 1 |
The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites Drug Metab Dispos. 2020 Nov;48(11):1113-1120. doi: 10.1124/dmd.120.000188.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
