| General Information of Drug Metabolite (DM) (ID: DM003192) |
| DM Name |
FRC-8653 Metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A (CYP3A)
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DMEN065
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| Oxidation - Dehydrogenation |
FRC-8653
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| FRC-8653 |
DR0323
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Phase 3 |
Essential hypertension |
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| References |
| 1 |
Metabolism and metabolic inhibition of cilnidipine in human liver microsomes. Acta Pharmacol Sin. 2003 Mar;24(3):263-8.
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