Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM003235)
DM Name	Noresketamine

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2B6 (CYP2B6)	DME0020	JNJ-54135419	Oxidation - N-demethylation	JNJ-54135419	[1]
Cytochrome P450 2C9 (CYP2C9)	DME0019	JNJ-54135419	Oxidation - N-demethylation	JNJ-54135419	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	JNJ-54135419	Oxidation - N-demethylation	JNJ-54135419	[1]
Mephenytoin 4-hydroxylase (CYP2C19)	DME0021	JNJ-54135419	Oxidation - N-demethylation	JNJ-54135419	[1]

Full List of Drug(s) That Produce This DM By Metabolism
JNJ-54135419		DR0621	Phase 3		Depression

References
1	PubChem : JNJ-54135419

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