| General Information of Drug Metabolite (DM) (ID: DM003277) |
| DM Name |
M18.4
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Conjugation - Glucuronidation |
LCQ908-NXA
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[1] , [2] |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Conjugation - Glucuronidation |
LCQ908-NXA
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[1] , [2] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
LCQ908-NXA
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| LCQ908-NXA |
DR1877
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Phase 3 |
Hypertriglyceridaemia |
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| References |
| 1 |
Pradigastat disposition in humans: in vivo and in vitro investigations. Xenobiotica. 2017 Dec;47(12):1077-1089.
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| 2 |
#N/A
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