Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM003363)
DM Name	AG-1549 Metabolite C11

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 3A1 (Cyp3a1)	DMEN096	AG-1549 Metabolite C18	Oxidation - Oxidationn	AG-1549	[1]
Cytochrome P450 3A1 (Cyp3a1)	DMEN096	AG-1549 Metabolite C22	Unclear - Unclear	AG-1549	[1]
Cytochrome P450 3A1 (Cyp3a1)	DMEN096	AG-1549 Metabolite C4	Unclear - Unclear	AG-1549	[1]
Cytochrome P450 3A1 (Cyp3a1)	DMEN096	AG-1549 Metabolite C18	Unclear - Unclear	AG-1549	[1]
Cytochrome P450 3A2 (Cyp3a2)	DMEN097	AG-1549 Metabolite C18	Oxidation - Oxidationn	AG-1549	[1]
Cytochrome P450 3A2 (Cyp3a2)	DMEN097	AG-1549 Metabolite C22	Unclear - Unclear	AG-1549	[1]
Cytochrome P450 3A2 (Cyp3a2)	DMEN097	AG-1549 Metabolite C4	Unclear - Unclear	AG-1549	[1]
Cytochrome P450 3A2 (Cyp3a2)	DMEN097	AG-1549 Metabolite C18	Unclear - Unclear	AG-1549	[1]

Full List of Drug(s) That Produce This DM By Metabolism
AG-1549		DR0267	Phase 1		Human immunodeficiency virus infection

References
1	Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs

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