General Information of Drug Metabolite (DM) (ID: DM004239)
DM Name
ICYS
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Dehydropeptidase-I (DPEP1) DME0117 Unclear - Unclear Ibrutinib [1]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
N-Acetyl transferases (NATF) DMEN228 Unclear - Unclear Ibrutinib [1]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004 Unclear - Unclear Ibrutinib [1]
Full List of Drug(s) That Produce This DM By Metabolism
Ibrutinib DR0843 Approved Mantle cell lymphoma
References
1 Extrahepatic metabolism of ibrutinib

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.