| General Information of Drug Metabolite (DM) (ID: DM005162) |
| DM Name |
Remdesivir Nucleoside Triphosphate
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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8-oxo-dGDP phosphatase NUDT18 (NUDT18)
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DMEN258
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| Hydrolysis - Hydrolysis |
Remdesivir
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[1] |
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8-oxo-dGDP phosphatase NUDT18 (NUDT18)
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DMEN258
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| Hydrolysis - Hydrolysis |
Remdesivir
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Remdesivir |
DR5430
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Approved |
Coronavirus Disease 2019 (COVID-19) |
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| References |
| 1 |
Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir
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