Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM005794)
DM Name	Ticrynafen S-oxide
Structure
Structure	3D MOL is unavailable			2D MOL is unavailable

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2C8 (CYP2C8)	DME0018	Tienilic acid	Oxidation - Oxidationn	Tienilic acid	[1]
Cytochrome P450 2C9 (CYP2C9)	DME0019	Tienilic acid	Oxidation - Oxidationn	Tienilic acid	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Tienilic acid		DR1593	Phase 4		Congestive heart failure

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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