| General Information of Drug Metabolite (DM) (ID: DM005953) |
| DM Name |
Ataluren-O-1beta-acyl glucuronide
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Conjugation - Conjugation |
PTC-124
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| PTC-124 |
DR0149
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Phase 3 |
Cystic fibrosis |
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| References |
| 1 |
Ataluren pharmacokinetics in healthy Japanese and Caucasian subjects. Clin Pharmacol Drug Dev. 2019 Feb;8(2):172-178.
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| 2 |
LC-MS/MS quantification of ataluren and ataluren acyl glucuronide in human plasma/urine: application in clinical studies
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