| General Information of Drug Metabolite (DM) (ID: DM006031) |
| DM Name |
NLA-715
|
| PubChem CID |
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2A6 (CYP2A6)
|
DME0005
|
| Oxidation - Hydrolyzationn |
WY-1485
|
[1] , [2] |
|
Cytochrome P450 2B6 (CYP2B6)
|
DME0020
|
| Oxidation - Hydrolyzationn |
WY-1485
|
[1] , [2] |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - Hydrolyzationn |
WY-1485
|
[1] , [2] |
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME0021
|
| Oxidation - Hydrolyzationn |
WY-1485
|
[1] , [2] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| WY-1485 |
DR0348
|
Phase 3 |
Haemorrhagic stroke |
|
|
| References |
| 1 |
BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification
|
| 2 |
Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
