Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM006156)
DM Name	Dabrafenib mesylate Metabolite M26

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 3A4 (CYP3A4)	DME0001	M31-Dabrafenib	Unclear - Unclear	Dabrafenib mesylate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Dabrafenib mesylate		DR0403	Approved		Melanoma

References
1	Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation

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