| General Information of Drug Metabolite (DM) (ID: DM006729) |
| DM Name |
ARQ-501 M4-1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Quinone reductase 1 (NQO1)
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DME0097
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| Multi-steps Reaction - Reduction; glucuronidation |
ARQ-501
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| ARQ-501 |
DR1869
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Phase 2 |
Leiomyosarcoma |
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| References |
| 1 |
Metabolic profile, enzyme kinetics, and reaction phenotyping of -lapachone metabolism in human liver and intestine in vitro
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