| General Information of Drug Metabolite (DM) (ID: DM006848) |
| DM Name |
CYC-202 M6
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Conjugation - Glucuronidation |
CYC-202
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[1] |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Conjugation - Glucuronidation |
CYC-202
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[1] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
CYC-202
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| CYC-202 |
DR1858
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Phase 2 |
Lung cancer |
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| References |
| 1 |
Metabolism of the trisubstituted purine cyclin-dependent kinase inhibitor seliciclib (R-roscovitine) in vitro and in vivo. Drug Metab Dispos. 2008 Mar;36(3):561-70.
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