| General Information of Drug Metabolite (DM) (ID: DM006857) |
| DM Name |
E-6005 M11
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Carboxylesterase (CES)
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DMEN121
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| Hydrolysis - Hydrolyzation |
E-6005
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| E-6005 |
DR1841
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Phase 2 |
Atopic dermatitis |
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| References |
| 1 |
Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: results of a randomized, vehicle-controlled, multicenter clinical trial. J Dermatol. 2014 Jul;41(7):577-85.
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