| General Information of Drug Metabolite (DM) (ID: DM007029) |
| DM Name |
6-hydroxylation of sabeluzole
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - 6-hydroxylation |
R-58735
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| R-58735 |
DR1798
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Discontinued |
Cerebral ischaemia |
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| References |
| 1 |
Pharmacokinetics of sabeluzole and dextromethorphan oxidation capacity in patients with severe hepatic dysfunction and healthy volunteers. Br J Clin Pharmacol. 2001 Feb;51(2):164-8.
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