Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM014817)
DM Name
Arsenous acid (AsIII)
Synonyms
Arsenous acid|arsorous acid|13464-58-9|TRIHYDROXYARSENITE(III)|arsenous trioxide|diarsonic trioxide|arsenic trihydroxide|arsenic (III) trioxide|H3AsO3|As(OH)3|Arsenious acid (H3AsO3)|UNII-935XD1L5K2|CHEBI:49900|935XD1L5K2|rubidium dihydroorthoarsenate|Arsenic (white)|trioxoarsenic acid|trihydroxidoarsenic|Arsenic oxide (3)|AArsenite (AsO33-)|Arsenous acid ion(3-)|AsH3O3|arsenous oxide anhydride|As-H3-O3|[As(OH)3]|trihydrogen trioxoarsenate(3-)|ARSENOUS ACID (H3ASO3)|CHEMBL1236189|DTXSID7074828|ARSENIOUS OXIDE, 99.999%|DB04456|LS-21725|LS-182058|Q423271
Pharmaceutical Properties Molecular Weight 125.944 Topological Polar Surface Area 60.7
Heavy Atom Count 4 Rotatable Bond Count 0
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 3
PubChem CID
545
Complexity
8
Formula
AsH3O3
Canonical SMILES
O[As](O)O
InChI
InChI=1S/AsH3O3/c2-1(3)4/h2-4H
InChIKey
GCPXMJHSNVMWNM-UHFFFAOYSA-N
IUPAC name
arsorous acid
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Arsenite methyltransferase (AS3MT) DME0408
Monomethylarsonic acid(MMAV)
Conjugation - O-methylation Arsenic trioxide [1] , [2] , [3]
Full List of Drug(s) That Produce This DM By Metabolism
Arsenic trioxide DR5412 Approved Mantle cell lymphoma
References
1 Type 2 diabetes affects arsenic metabolism via transporters in arsenic trioxide treated acute promyelocytic leukemia patients
2 Biotransformation of arsenic trioxide by AS3MT favors eradication of acute promyelocytic leukemia: revealing the hidden facts
3 LABEL:ARSENIC TRIOXIDE injection

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