| General Information of Drug Metabolite (DM) (ID: DM015947) |
| DM Name |
RS-88390 (CVT-2514)
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| Structure |
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3D MOL
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2D MOL
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| PubChem CID |
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - O-demethylation |
Ranolazine
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[1] , [2] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - O-demethylation |
Ranolazine
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Ranolazine |
DR1394
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Approved |
Angina pectoris |
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| References |
| 1 |
Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions
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| 2 |
Fatal, Intentional Overdose of Ranolazine: Post-Mortem Distribution of Parent Drug and its Major Metabolite
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