| General Information of Drug Metabolite (DM) (ID: DM017132) |
| DM Name |
Hydroxyvitamin K1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 4F2 (CYP4F2)
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DME0025
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| Oxidation - Hydroxylation |
Phytonadione
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[1] , [2] , [3] , [4] , [5] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Phytonadione |
DR5202
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Approved |
Vitamin K deficiency |
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| References |
| 1 |
Metabolism of vitamin K1 (phylloquinone) in man
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| 2 |
Vitamin K nutrition, metabolism, and requirements: current concepts and future research
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| 3 |
Dietary reference values for vitamin K
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| 4 |
Preparative isolation and characterization of the urinary aglycones of vitamin K1 (phylloquinone in man
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| 5 |
Cytochrome P450-dependent catabolism of vitamin K: -hydroxylation catalyzed by human CYP4F2 and CYP4F11
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