Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM017258)
DM Name	PF-00734200 metabolite M5
Structure
Structure	3D MOL is unavailable			2D MOL is unavailable

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2D6 (CYP2D6)	DME0009	PF-00734200	Unclear - Unclear	PF-00734200	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	PF-00734200	Unclear - Unclear	PF-00734200	[1]

Full List of Drug(s) That Produce This DM By Metabolism
PF-00734200		DR3192	Phase 2		Type-2 diabetes

References
1	Metabolism, excretion, and pharmacokinetics of ((3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a dipeptidyl peptidase inhibitor, in rat, dog and human

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