| General Information of Drug Metabolite (DM) (ID: DM017363) |
| DM Name |
Tesofensine metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - N-desalkylation |
Tesofensine
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Tesofensine |
DR3260
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Phase 2 |
Pain |
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| References |
| 1 |
Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease
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