| General Information of Drug Metabolite (DM) (ID: DM017712) |
| DM Name |
Ebastine Metabolite M-3
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 4F2 (CYP4F2)
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DME0025
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| Unclear - Unclear |
Ebastine
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Ebastine |
DR0557
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Phase 4 |
Irritable bowel syndrome |
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| References |
| 1 |
Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes
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| 2 |
Identification of rat faecal metabolites of ebastine by B/E linked scanning liquid secondary ion mass spectrometry
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