| General Information of Drug Metabolite (DM) (ID: DM017791) |
| DM Name |
Rolafagrel Metabolite A
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Beta-glucuronidase (GUSB)
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DME0106
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| Unclear - Unclear |
Rolafagrel
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Rolafagrel |
DR2966
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Discontinued in Phase 2 |
Nephritis |
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| References |
| 1 |
In vivo glucuronidation in rat and humans of 5,6-dihydro-7-(1H-imidazol-1-yl)-naphthalene-2-carboxylic acid, a selective inhibitor of thromboxane synthase
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