Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM017798)
DM Name
Napitane mesilate Metabolite M4
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Catechol O-methyltransferase (COMT) DME0043
Napitane mesilate Metabolite M1
Unclear - Unclear Napitane mesilate [1]
Full List of Drug(s) That Produce This DM By Metabolism
Napitane mesilate DR2988 Discontinued in Phase 2 Major depressive disorder
References
1 Implication of P450-metabolite complex formation in the nonlinear pharmacokinetics and metabolic fate of (+/-)-(1'R*,3R*)-3-phenyl-1-[(1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in dogs

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