| General Information of Drug Metabolite (DM) (ID: DM017842) |
| DM Name |
RO2433-MP
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Deoxycytidylate deaminase (DCTD)
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DME0112
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| Unclear - Unclear |
R7128
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Uridine/cytidine monophosphate kinase (UMPK)
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DME0456
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| Unclear - Unclear |
R7128
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| R7128 |
DR2937
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Discontinued in Phase 2 |
Hepatitis C virus infection |
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| References |
| 1 |
Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species
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