Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM017912)
DM Name	Rilpivirine M5

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
UDP-glucuronosyltransferase 1A4 (UGT1A4)	DME0048	Rilpivirine hydrochloride	Conjugation - Glucuronidation	Rilpivirine hydrochloride	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Rilpivirine hydrochloride		DR1424	Approved		Human immunodeficiency virus infection

References
1	Human biotransformation of the nonnucleoside reverse transcriptase inhibitor rilpivirine and a cross-species metabolism comparison. Antimicrob Agents Chemother. 2013 Oct;57(10):5067-79.

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