| General Information of Drug Metabolite (DM) (ID: DM018030) |
| DM Name |
Ambrisentan glucuronide
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Conjugation - Glucuronidation |
Ambrisentan
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[1] |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Conjugation - Glucuronidation |
Ambrisentan
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[1] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
Ambrisentan
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Ambrisentan |
DR0080
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Approved |
Pulmonary hypertension |
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| References |
| 1 |
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan. J Clin Pharmacol. 2009 Jun;49(6):719-24.
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