| General Information of Drug Metabolite (DM) (ID: DM018110) |
| DM Name |
Methotrexate?polyglutamates
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Folylpolyglutamate synthase (FPGS)
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DME0191
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| Unclear - Unclear |
Methotrexate
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Methotrexate |
DR1045
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Approved |
Breast cancer |
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| References |
| 1 |
Measuring methotrexate polyglutamates
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| 2 |
Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms
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