| General Information of Drug Metabolite (DM) (ID: DM018177) |
| DM Name |
PU-H71 Metabolite M2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Catechol O-methyltransferase (COMT)
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DME0043
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| Oxidation - O-demethylation |
PU-H71
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| PU-H71 |
DR3102
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Phase 1 |
Breast cancer |
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| References |
| 1 |
First-in-human study of the epichaperome inhibitor PU-H71: clinical results and metabolic profile
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